Ceraxon for delayed speech development: effective or not?

General characteristics of the drug

Ceraxon is a nootropic drug that has a beneficial effect on the cognitive functions of the brain. Its spectrum of action is wide:

• improvement of memory and thought processes;
• increasing the brain’s resistance to adverse effects (trauma, hypoxia, infections, intoxication);
• preventing the death of damaged brain cells;
• reduction of cerebral edema;
• restoration of self-care skills and volitional qualities after severe diseases of the nervous system

For adults, the medication is indicated during the recovery period after a stroke, traumatic brain injury, and for vascular and degenerative pathologies of the brain.

Pharmacological properties of the drug Ceraxon

Citicoline stimulates the biosynthesis of structural phospholipids in neuronal membranes, which improves membrane function, including the functioning of ion exchange pumps and neuroreceptors. Due to its stabilizing effect on the membrane, citicoline has anti-edematous properties and reduces cerebral edema. Citicoline reduces the severity of symptoms of cerebral dysfunction after pathological processes such as traumatic brain injury or acute cerebrovascular accidents. Citicoline reduces the level of amnesia, improves the condition of cognitive, sensory and motor disorders, and also weakens the severity of symptoms that are observed with hypoxia and cerebral ischemia, including memory impairment, emotional lability, and impaired ability to perform normal self-care activities. Citicoline is a natural compound found in the human body, so classical pharmacokinetic studies cannot be performed due to the difficulty of quantifying exogenous and endogenous citicoline. During a pharmacokinetic study, its almost complete absorption in the gastrointestinal tract was determined - less than 1% of the dose taken was detected in the feces within 5 days after taking the drug. Two peaks of radioactivity were also noted in the blood plasma, due to metabolism in the liver and intestines: the first - after 1 hour, the second - after 24 hours. Bioavailability by oral and parenteral routes of administration is almost the same. Excretion is very slow, mainly through the respiratory system and urine. After 5 days of administration, about 16% of the drug dose was detected, which indicates the inclusion of the rest of the dose in metabolic processes.

Does Cerakson help with RRR in children?

For children, the drug is indicated for:

• perinatal encephalopathy (traumatic, toxic effects in utero, during childbirth, in the first year of life);
• delayed psychophysical development;
• emotional disorders;
• speech development delay (SDD).

In case of delayed speech development caused by psychogenic disorders - separation from mother, placement of the child in a boarding school, 24-hour kindergarten, long-term illness - the help of a psychologist is necessary.

If RRR is caused by encephalopathy, vascular disorders of the brain, the effectiveness of the drug is undeniable. It activates speech centers in the cerebral cortex and improves auditory perception. The medication has a beneficial effect on the development of cognitive functions (memory, attention, thinking), which indirectly contribute to the development of speech.

Mechanism of action of Cerakson in ZRR

In case of RRD of organic origin (caused by brain damage due to toxic and/or traumatic effects on the fetus during pregnancy, childbirth or on the brain of the newborn), the nootropic effect of the drug is expressed in:

• restoration of damaged neurocytes;
• improving the transmission of impulses in brain tissue;
• preventing the formation of free radicals, leading to additional intoxication of the brain, the development of vascular and degenerative pathologies;
• suppression of the action of phospholipase enzymes involved in the process of cell damage.

Is Cerakson allowed for children under one year of age?

Research in recent years has shown that the medicine can be safely prescribed to babies up to one year old. For children, there is now a special release form of Ceraxon - in the form of a strawberry-flavored syrup. For infants, the medicine is indicated for:

• intrauterine hypoxia;
• hypoxia during childbirth, caused by obstruction of the birth canal and delayed first breath;
• premature

The results of using the medication in children under one year of age revealed a significant improvement in the psycho-emotional state and normalization of psychophysical development.

Ceraxon: instructions for use for children

Doses of the drug depend on the severity of the damage to the central nervous system, the stage of delayed speech development, age, body weight, degree of prematurity of the child, characteristics of the nervous system, and individual response to the drug. Only the doctor selects the dosage for each small patient! Approximate treatment regimen:

Up to
a year .
It is preferable to administer in the form of syrup, but in some cases intramuscular injections are also used. The required dose of syrup is measured with a special syringe located in the package and mixed with a small amount of breast milk or artificial formula. Give 30 minutes to 1 hour after feeding. The course of treatment is 3 months. If necessary, after 3-6 months. the course is repeated. The duration of the course is determined only by the attending physician! Dosages by month for babies under one year of age are presented in Table 1.

Table 1. Dosages of Ceraxon for babies under one year old

After
a year,
the drug is used in the form of syrup, tablets, suspension, injections. The form of use, dose, frequency and duration of treatment is determined only by a doctor! Table 2 shows approximate doses of the medication for children 1 year old – 14 years old.

Table 2. Doses of Ceraxon for children of different ages

Side effects in children

As practice shows, adverse reactions in children occur extremely rarely. There may be individual intolerance to syrup components (for example, fructose). In this case, it is necessary to change the form of the drug - give injections or give suspensions. After three years, you can use the tablet form.

Cerakson is not prescribed to children with a predominance of the parasympathetic type of the central nervous system: it can provoke nausea, vomiting, diarrhea, headache, shortness of breath, redness of the skin, tremor, and swelling. Sometimes hallucinations are possible.

All symptoms are quickly relieved by symptomatic therapy. But you can’t do anything on your own! If such phenomena occur, you should immediately consult a doctor!

The drug is not recommended to be prescribed simultaneously with other nootropics, in particular with Meclofenoxate. Ceraxon also enhances the effect of the antiparkinsonian drug Levodopa.

Reviews from parents about Tserakson

Numerous reviews from parents prove the high effectiveness of the use of Ceraxon for cervical cancer.

Anna: We live in a small town, we don’t have the opportunity to visit a psychologist or speech therapist. The doctor prescribed Ceraxon. Drank for 6 months. Before treatment, the child was silent and did not utter a single sound. Six months later he speaks entire sentences!

Vadim: We took the drug for 1.5 months. The child began to answer questions, so far only “yes” and “no”, we hope for further progress. Does not cause allergies, is well tolerated.

Lena: We’ve been taking the medicine for 5 months. In addition to the fact that the child started talking, he became interested in what was happening, he began to dress himself, eat, and tries to draw something. My daughter drinks with pleasure. The drug has a pleasant taste.

Marina: My son is 4 months old. Born with hypoxia. We take Ceraxon for a month. Before him, my son cried all the time, was very restless, and did not latch on to the breast. Now he is smiling, calm, sleeps well, and walks.

Among the disadvantages of the drug, parents note only the high price and rare adverse reactions.

Thus, Cerakson can be safely prescribed to children of any age with gastrointestinal development of organic origin. Important !

It should be remembered that the treatment must be completely carried out by a specialist! Independently selecting, changing the dose, method of administration, setting the regimen and duration of the course of treatment is strictly prohibited!

Alina Veyts, psychoneurologist, candidate of psychological sciences, especially for Mirmam.pro

Special instructions for the use of the drug Ceraxon

There are no age restrictions for oral use of the drug. Pregnancy and lactation Although no evidence of risk to the fetus has been obtained when using the drug, during pregnancy the drug is used only when the expected benefit outweighs the potential risk. There are no data on the passage of citicoline into breast milk and its effect on the fetus is unknown. Effect on the ability to drive vehicles and operate complex mechanisms. Citicoline does not affect the ability to drive vehicles and operate complex mechanisms.

Comparison of the effectiveness of Encephabol and Ceraxon

The effectiveness of Encephabol is quite similar to Ceraxon - this means that the ability of the drug substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Encephabol is more pronounced, then using Ceraxon even in large doses will not achieve this effect.

Also, the speed of therapy - an indicator of the speed of therapeutic action - is approximately the same for Encephabol and Ceraxon. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.

Comparison of addiction between Encephabol and Ceraxon

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values ​​of such parameters as “o syndrome” in Encephabol is quite similar to the similar values ​​in Ceraxon. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, in Encephabol the values ​​of the “syndrome” are quite small, however, the same as in Ceraxon.

Comparison of side effects of Encephabol and Ceraxon

Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.

Encephabol has almost the same level of adverse events as Ceraxon. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Encephabol are similar to Cerakson: how quickly the body recovers after taking it and whether it recovers at all.

Comparison of the safety of Encephabol and Ceraxon

The safety of a drug includes many factors.

At the same time, in Encephabol it is quite similar to Ceraxon. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Encephabol, as well as of Ceraxon, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Encephabol does not have any risks when used, just like Ceraxon.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Encephabol and Ceraxon.