Glycine, Afobazol or Novopassit which is better, review of drug analogues

For anxiety disorders, the question often arises about what is better to take: Persen or Novopassit, since both drugs have a similar effect and eliminate the effects of stress. These medications calm and normalize sleep.

For anxiety disorders, you can take Persen or Novopassit.

Description of Glycine

Glycine is a nootropic drug, the main active substance is an amino acid. It is necessary for the development and proper functioning of the human body. The amino acid has many important functions, but the most important is maintaining the normal functioning of the nervous system.

Glycine is used for stressful situations, physical and mental stress, insomnia, neuroses, and depression.

Effect of the drug on the body:

relieves irritability and aggression;
normalizes sleep;
reduces the inhibitory effect on the nervous system provoked by alcoholic beverages;
stimulates mental activity;
Read also: Treatment of Post-Traumatic Stress Disorder
restores cerebral blood supply.

The medication is produced in the form of lozenges. The dosage is 4-6 pcs. per day for a month. This component, natural to the body, almost never causes negative effects or overdose. The drug is allowed for infants, adults and elderly patients. Can be used during pregnancy and breastfeeding. It is indicated with extreme caution in patients with arterial hypotension, since taking Glycine often increases blood pressure.

For diseases of the cardiovascular system, accompanied by increased blood pressure, it is important to choose an antihypertensive drug that has few side effects. Read more in the article: “lozap and lisinopril: analogues and replacement.”

Release forms and price

Persen is produced in Switzerland in the following dosage forms:

tablets, 20 pcs. – 249 rub.;
40 pieces – 384 rubles;
60 pieces – 501 rubles;
capsules (Persen night), 10 pcs. – 254 rub.;
20 pieces – 404 rubles;
40 pieces – 614 rubles.

Novo-Passit from Israel is available in pharmacies in the following varieties:

tablets, 10 pcs. – 208 rub.;
30 pieces – 409 rubles;
60 pieces – 610 rubles;
solution, 100 ml – 205 rub.;
200 ml – 316 rubles.

Characteristics of Afobazole

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Afobazole is a tranquilizer that exhibits a calming effect without suppressing the central nervous system. The main active ingredient is fabomotizole, which is a selective anxiolytic. The drug is effective for various psycho-emotional disorders and depression.

Afobazole is recommended for people with somatic, dermatological pathologies, and oncology.

Indications for use:

cardiopsychoneurosis;
anxiety, neurasthenia;
sleep disturbance;
mood change, adaptation.

Afobazole contraindications and negative effects:

period of breastfeeding, pregnancy;
individual intolerance to constituent substances;
patients under 18 years of age.

Adverse effects are extremely rare. In case of overdose, drowsiness, general malaise, and weakness appear. Activated carbon or gastric lavage will help eliminate this condition.

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Dosage of the drug: a single dose is 10 mg, the therapeutic course is 3-4 weeks three times a day after meals. To restore sleep, up to 60 mg is prescribed. Afobazole helps eliminate alcohol syndrome and improves well-being when quitting smoking.

Capoten and Captopril are drugs for the symptomatic treatment of hypertension. They do not eliminate the causes of the disease, but only reduce blood pressure and maintain its normal levels, provided they are taken systematically. Read more in the article: “what is the difference between capoten and captopril.”

What is the difference between novopassit and persen?

The modern rhythm of life negatively affects health and sometimes causes a malfunction of the autonomic nervous system. Sedatives will help restore its functioning and normalize the lost balance in the body. In such cases, Novopassit or Persen are often taken.

Novopassit or Persen will help normalize the lost balance in the body.

Compound similarities

The similar medicinal properties of drugs are due to their composition. The presence of 2 main common components gives an almost identical effect when treated with drugs.

Valerian extract has a diverse effect on the body. As a result of its use, positive changes occur in the functioning of many organs and systems:

Digestion is improved, the functioning of the intestinal tract is normalized, bile secretion increases;
blood vessels dilate, cardiac activity improves;
emotional balance is restored, the level of worry and anxiety is reduced, and performance increases.

Melissa extract relieves spasms and has a stimulating effect on brain function. The calming effect of the herb on the body leads to the elimination of headaches and migraines, and normalization of sleep.

Differences between Novopassit and Persen

Some differences in the characteristics of medicinal substances are also due to their composition.

The effect of Novopassit is stronger. It has a wider range of therapeutic qualities, because... it contains additional plant substances:

Common hops. Refers to antispasmodic and hypnotic herbal remedies. Helps improve the functioning of the cardiovascular system.
St. John's wort. Gives antidepressant and anxiolytic effects. Under its influence, nervous tension is eliminated, the emotional background increases, and mental stability increases.
Hawthorn. Helps improve blood circulation in the heart muscle. Reduces blood pressure and has a mild sedative effect.
Black elderberry flowers. Provides diuretic and analgesic effects.
Passionflower herb. Has a moderate sedative effect.

Persen's composition includes peppermint, which is used not only as a sedative, but also to provide a choleretic effect. In this regard, the drug has additional contraindications for use.

It is not recommended for use in urolithiasis. The disease is characterized by the formation of stones in the bile ducts. Eating peppermint can cause stones to block the ducts.

Use Persen with caution for peptic ulcers and esophagitis.

The drugs also differ in price. The cost of Novopassit is higher.

Which is better - Novopassit or Persen

Each of the medications has an effective sedative effect on the body and helps eliminate disturbing symptoms.

The choice of a therapeutic agent must be approached individually, based on the result and your internal feelings. Due to the difference in composition, drugs may be tolerated differently by the body and have different side effects.

Reviews from doctors

Valery (therapist), 43 years old, Moscow

The sedatives Novopassit and Persen, which have natural ingredients in their composition, are practically safe for health. They effectively reduce the excitability of the nervous system and eliminate spasms in muscles and organs.

Olesya (neurologist), 47 years old, Ufa

There is a positive effect of these drugs on the heart and normalization of sleep. During treatment, the balance of excitation and inhibition processes in the body improves. But at the same time, it is necessary to comply with all medical recommendations, because Even as a result of using natural medicines, side effects may develop.

Patient reviews of Novopassit and Persen

Larisa, 46 years old, Saransk

Novopassit is in the medicine cabinets of many of my friends and relatives. The product is natural and helps well with stressful situations and sleep problems. It has a gentle effect on the body, but the effect of taking it is short-lived.

Some friends note that the drug is rather weak, so you should not count on it if you have severe neuroses and disorders of the nervous system.

Kristina, 29 years old, Perm

I used the medicine for vegetative-vascular dystonia. For a long period of time she suffered from increased weakness and headaches. I was always afraid to use strong medications, so I refused the recommended treatment.

A friend advised me to try a course of treatment with Novopassit. She herself has been taking a nerve calmer for a long time and says that it works.

I drank the medicinal syrup for a month, and the result was surprising. The condition has improved, and some symptoms have gone away completely. The product is good and the price is low.

Roman, 32 years old, Krasnodar

A few months ago I began to get very irritated, nervous, and my hands began to tremble. Previously, I fell asleep instantly, but when my condition worsened, I began to have difficulty falling asleep and tossed and turned in bed for a long time. I woke up many times during the night.

The doctor recommended Persen. I doubted its effectiveness, but still tried it. My sleep returned to normal and I began to feel calmer. The drug helps with nerve problems.

Valeria, 38 years old, Ufa

I can’t classify myself as a calm person. I often fall into depression and despondency, accompanied by increased anxiety and irritability. I try to use sedative medications that are less harmful to the body. Previously, I carried out courses of treatment with glycine on the advice of a doctor, but over time it stopped helping. I switched to Novopassit.

The drug has a stronger effect on the body. The effect is felt almost instantly. After drug therapy, positive changes in the state of the nervous system are observed. The product is very calming and improves sleep.

Source: https://schitovidka03.ru/lecheniye/lekarstva/novopassit-ili-persen

Features of Novopassit

Novopassit is a sedative medicine of plant origin. Main ingredients: lemon balm, St. John's wort, hops, valerian, hawthorn. Additional components: glycerol, cellulose, magnesium stearate. Effective for:

feeling irritable;
chronic fatigue;
memory loss;
sleep disturbance.

The drug exhibits a slight sedative effect and has an antispasmodic effect when feeling pain or spasms.

Novopassit is produced in syrup, tablet form, and liquid extract. Directions for use: 1-2 tablets. three times a day, solution - 5-7 drops. 3 times. Since Novopassit is based on plant elements, it has almost no contraindications or adverse effects. It is allowed for pregnant and lactating women, as well as patients over 12 years of age. The only side effects are allergies to substances, rarely - nausea, heartburn, indigestion. Not used for epilepsy, bradycardia. It is forbidden to combine Novopassit with alcohol.

Other information

The drug should be stored at room temperature. Shelf life – 36 months from the date of release. Sold in pharmacies without a doctor's prescription.

Before taking Persen, you need to familiarize yourself with the features of its action and in what cases the tablets will be effective. If during therapy the symptoms do not disappear or the condition becomes even more severe, then you need to seek help from a specialist.

In patients with gastroesophageal reflux disease, the condition may only worsen during treatment.

After taking the pills, it is better to stop driving a vehicle and other dangerous mechanisms.

The duration of the treatment course should not exceed 60 days. If negative reactions occur, you should immediately inform a specialist.

Afobazole or Glycine - which is better?

Which remedy to use depends on the severity of the symptoms. For severe anxiety, it is better to use Afobazole. In case of simple nervous overexcitation or irritability, preference can be given to Glycine. It is also effective at the time of intellectual stress; Afobazole does not increase cognitive abilities.

Glycine is allowed for children and women during pregnancy; Afobazole is contraindicated in these groups.

Similarities of drugs:

medications affect the nervous system and exhibit a sedative effect, but Afobazole has a more intense anti-anxiety effect;
occasionally lead to negative phenomena;
both medications reduce symptoms of depressive disorder and help cope with insomnia;
the products do not increase the effects of alcoholic beverages.

These drugs can be used in combination; their compatibility does not cause adverse events. If treatment is carried out with two means, then the interval between them is at least 30 minutes.

Patients' opinions

Oleg, 47 years old, Tuymazy

I took both drugs at different times. I think Novopassit is more effective, although it often causes nausea. After a week of taking it, I felt that I became less nervous. I periodically repeat the course of treatment.

Larisa, 39 years old, Samara

I take Persen periodically for preventive purposes. Sometimes itching is caused by nervousness, and the medication perfectly eliminates such unpleasant symptoms. However, to notice the result, you need to take the medicine for at least a month.

Valentina, 63 years old, Moscow

For insomnia, I resort to taking Novopassit. The drug helps you fall asleep faster, although the effect does not appear immediately. Sometimes it is necessary to take the medicine for at least 1-2 weeks in order for sleep to normalize.

Novopassit or Glycine - what to choose?

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When purchasing a product, you must rely on the effect expected from use. When the body lacks an amino acid, Glycine can fill it. Mainly used by students and preschoolers to increase mental and physical activity. Also indicated for elderly patients to restore sleep and improve memory. The drug is combined with Mexidol, Vinpocetine.

Similarities and differences:

They have the same effect on the body.
Both drugs are safe because they contain natural substances.
Novopassit is a sedative, Glycine is a nootropic agent. The first is a herbal medicine, the second is an amino acid.

For family troubles, nervousness at work and other life situations, doctors prescribe Novopassit. The product is not addictive compared to antidepressants, tranquilizers, and has natural ingredients that will help you achieve the desired result. Novopassit relieves anxiety, stress, and insomnia.

Pharmacology

Tablets are a medicinal product with a sedative and antispasmodic effect. Melissa, valearian and mint extract provides a calming and antispasmodic effect.

In general, after taking the drug there is a decrease in feelings of anxiety and nervousness. There is a noticeable improvement in the condition of people in an excited and emotional state. With insomnia, the patient falls asleep much easier and faster, sleeps more soundly, and does not feel drowsy throughout the day.

Persen has a general effect on the human body due to its constituent components. Therefore, no clinical studies have been conducted. It is not possible to determine the metabolites of the drug.

Afobazole or Novopassit - which is better?

Sedatives improve the functioning of the central nervous system. Both medications relieve symptoms, but affect the body differently.

Similarities and differences between them:

They have the same indications and contraindications (pregnancy, lactation).
The main difference is the chemical composition. Novopassit is created from plant substances, Afobazol is a synthetic medicine.
The price of Novopassit is 300-750 rubles, Afobazol - 350-400 rubles.

When choosing a product, it is necessary to take into account the age and well-being of the person. Depending on the physical activity or type of activity, one drug may be better or worse than another. Novopassit or Afobazol is better; according to doctors, the first has a more delicate effect on the central nervous system, is well tolerated by people and rarely provokes negative reactions. However, for long-term treatment it is better to use Afobazole, but only under the supervision of a specialist.

Adverse reactions and overdose

When taking pills, negative reactions may occur in the form of:

allergies, manifested by hyperemia, bronchospasms and skin rash;
Long-term use may cause constipation.

Cases of overdose are possible. Usually happens if more than 60 tablets have been taken. Nausea, vomiting, lethargy, pain inside the body, and dizziness may occur. 24 hours after taking the drug in large quantities, the signs of overdose disappear. No toxic effects are observed. If necessary, you can do symptomatic treatment.

Analogues of sedatives

If for some reason the patient cannot take the above medications, they can be easily replaced with others with a similar action and effect.

Table with similar drugs:

A drug	Active substance	Manufacturer	Price
Grandaxin	tofisopam	Hungary	from 369 rub.
Phenibut	aminophenylbutyric acid	Russia, Latvia, Belarus	from 149 rub.
Adaptol	mebicar	Latvia	from 1138 rub.
Phenazepam	bromodihydrochlorophenylbenzodiazepine	Russia Valenta FARM JSC	from 150 rub.
Tenoten	antibodies to brain-specific protein S-100	Russia Moscow	from 267 rub.
Picamilon	nicotinoyl gamma-aminobutyric acid	Russia	from 146 rub.
Piracetam	piracetam	India	from 62 rub.
Cortexin	bovine cerebral cortex polypeptides	Geropharm LLC	from 1321 rub.
Cerebrolysin	Cerebrolysin concentrate	Austria	from 1529 rub.
Atarax	hydroxyzine hydrochloride	Belgium	from 286 rub.

The drugs will help relieve feelings of fear, tension and anxiety.

Persen is an effective drug

Persen is a sedative of plant nature; several main components predominate in its composition: lemon balm, mint, valerian. The medicinal properties and pharmacological effects of the drug are due to its natural components. The drug has an antispasmodic, calming effect and has a slight effect on the nervous system. Persen is effective for:

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increased nervous excitability;
sleep disturbance;
irritability, depression.

You should not take the medicine if you have:

intolerance to lactose, fructose;
children under 12 years of age;
lactation, pregnancy;
susceptibility to constituent substances;
tendency to increase blood pressure;
gallstone pathology;
lack of lactase in the body.

Mint, which is part of the medication, has a vasoconstrictive effect on the blood vessels of the brain. The drug is often used for VSD and insomnia. Since Persen contains natural substances, it is not addictive.

Grandaxin is an effective tranquilizer

Grandaxin has an anxiolytic effect and almost no anticonvulsant or sedative effect. The medicine is considered a psycho-vegetative regulator and helps get rid of autonomic disorders. Shows moderate stimulating ability. Due to the lack of muscle relaxant results, the drug can be used in patients with myasthenia gravis and myopathy.

Grandaxin is a “daytime” medication, that is, it does not cause drowsiness, addiction or withdrawal symptoms.

Negative phenomena:

headache, severe irritability, confusion;
skin rash;
Read also: Anafranil® (Anafranil®)
muscle pain;
loss of appetite, abnormal stool, dry mouth.

The tablets should be used with caution for epilepsy, atherosclerosis, and closed-angle glaucoma. Not prescribed during lactation, 1st trimester of pregnancy. Directions for use: 1-2 tablets. three times a day for 3 weeks. The maximum daily dose is 300 mg.

Phenibut is an anti-anxiety drug

Phenibut is a nootropic medicine that has psychostimulating, antioxidant, and tranquilizing effects. Improves brain function by restoring tissue metabolism and improving cerebral circulation. The drug reduces or completely eliminates feelings of anxiety, tension, and improves sleep.

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Phenibut enhances the effect of narcotic analgesics, hypnotics and antipsychotic drugs. Indications for use:

nightmares in elderly patients;
psychopathy;
asthenic, neurotic conditions;
stuttering in children;
obsessive-compulsive neurosis;
additional remedy in the treatment of alcoholism.

The dose of Phenibut and duration are determined by individual characteristics, the age of the patient, and tolerability of the medication. A single dose of medication ranges from 20-750 mg - for adults; from 20-250 mg - for a child. It is indicated with special caution for liver failure and digestive diseases.

Adaptol is an analogue of Afobazole

The active component of Adaptol is tetramethyltetraazabicyclooctanedione, the release form is tablets. Relieves anxiety, worry, fear, internal psycho-emotional stress. The calming result is not associated with muscle relaxation or changes in motor coordination. It does not reduce motor or mental ability, therefore it is recommended for pupils, students and working people. Does not cause a feeling of euphoria.

It does not have a hypnotic effect, but it increases the effect of sleeping pills and improves sleep. Adaptol improves or eliminates nicotine withdrawal. In addition to the sedative, it produces nootropic assistance. Normalizes cognitive functions, attentiveness, does not stimulate signs of psychopathological disorders, namely delirium, excessive excitability.

Adaptol dosage: 500 mg three times a day, taken regardless of meals. The maximum dose is 10 g per day. The duration of therapy is up to 2 months.

Tenoten is an anxiolytic drug

Tenoten is a nootropic drug that provides anti-anxiety results without causing adverse muscle relaxant, hypnotic effects. Normalizes the tolerance of emotional stress. Shows antihypoxic, antidepressant, antiamnestic effects.

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In case of hypoxia or intoxication, Tenoten produces a neuroprotective effect, limiting the area of damage and improving memory. The drug should not be used by patients under 18 years of age or with high susceptibility to the constituent substances.

Directions for use: tablets should be taken before meals, 1-2 tablets. twice a day. If absolutely necessary, the frequency is increased up to 4 times. Since activating elements predominate in the drug, the last dose should be taken at least 2 hours before going to bed.

The therapeutic course is 1-3 months. If there is no improvement in the condition within 4 weeks, the patient should consult a doctor.

The difference between Persen and Novopassit

Characteristics of Persen

The drug is available in the form of tablets, which contain herbal extracts such as:

The medication relieves spasms and eliminates symptoms of anxiety, providing a mild calming effect. The medicine is used for sleep disorders, constant stress and emotional overload. The drug can be used during PMS to eliminate increased irritability, mood swings and aggression.

It is recommended to take the medication for no more than 6 weeks. There is no withdrawal syndrome, since the medicine contains only natural ingredients. Children over 12 years of age are allowed to receive therapy. Negative reactions occur rarely and manifest themselves in the form of itching, rashes and constipation.

The drug should not be taken if you have low blood pressure, constant lethargy or gallbladder disease. The medication can be used for therapy only after consultation with a gastroenterologist if there are pathologies associated with increased production of gastric juice.

The medicine affects the speed of reactions, so work that requires increased concentration should be approached with caution. If heartburn, stomach pain and nausea occur during therapy, it is recommended to discontinue the drug and replace it with another one.

It is not recommended to combine the medication with drugs that affect the central nervous system: antidepressants and anti-anxiety drugs.

Persen affects the speed of reactions, so work that requires increased concentration should be approached with caution.

Characteristics of Novopassit

The drug is available in the form of an oral solution and tablets. The medication contains guaifenesin, as well as medicinal plants:

passionflower;
St. John's wort;
lemon balm;
hawthorn;
hops and elderberry.

The medicine calms, eliminates anxiety and irritation, reduces emotional lability. The drug helps improve mood due to St. John's wort included in the composition.

The medication is effective for neurotic disorders, sleep disorders, as well as constant mental stress.

The medicine relieves headaches, gastrointestinal pathologies of psychosomatic etiology, nervous itching and symptoms of dystonia.

The medication is not prescribed for alcohol dependence, acute gastrointestinal diseases, muscle weakness, liver pathologies and central nervous system lesions.

It is better to take the medicine with food to avoid negative reactions from the stomach. Novopassit is approved for use in children over 12 years of age.

During treatment, symptoms such as:

nausea;
stomach pain;
stool disorders;
lethargy;
dizziness;
decreased speed of psychomotor reactions;
vomit;
allergy.

All unpleasant symptoms quickly disappear after completing the course of treatment.

The drug is not recommended to be combined with muscle relaxants, psychotropic medications and immunosuppressants. You should not drink alcohol during therapy. If the patient’s condition does not return to normal within a week, then you should consult a doctor.

During treatment with Novopassit, symptoms such as nausea and stomach pain may occur.

The components that make up the drug increase photosensitivity, so during treatment you should not sunbathe in the sun or visit a solarium.

Comparison of Persen and Novopassit

Both drugs have similar effects on the body, but there are also significant differences.

Similarities

Both medications are used for anxiety disorders and sleep disorders.

What is the difference

Novopassit contains not only natural ingredients, but also an anxiolytic. This drug also differs from Persen in a more extensive list of adverse reactions.

What is more effective

Both drugs are effective in the treatment of neurosis-like diseases. However, Novopassit is considered more effective.

Which is stronger

Novopassit has a stronger effect on the central nervous system.

Which is cheaper?

Novopassit is cheaper than Persen. Its cost starts from 190 rubles. Price for Persen - from 240 rubles.

Which is better: Persen or Novopassit

The effectiveness of medications depends on the disease for which they are used.

For hyperhidrosis

To eliminate excessive sweating of psychosomatic etiology, it is best to use Novopassit.

For neurosis

For neurosis-like pathologies, both drugs are equally effective. If the disease is accompanied by increased anxiety and panic attacks, then it is better to take Novopassit.

During pregnancy

During pregnancy, both medications are contraindicated.

For insomnia

For mild insomnia, you can take Persen. If sleep disturbances have been present for a long time, then preference should be given to Novopassit.

Patients' opinions

Oleg, 47 years old, Tuymazy

Larisa, 39 years old, Samara

Valentina, 63 years old, Moscow

Reviews from doctors about Persen and Novopassit

Ksenia, 32 years old, general practitioner, Krasnodar

I consider Novopassit more effective and recommend it more often. However, it also has more side effects than Persen. It is especially important to pay attention to the fact that such a medicine can provoke a worsening of gastrointestinal diseases associated with high acidity. In other cases, it does its job perfectly.

Alla, 44 years old, therapist, Syzran

I often prescribe Persen to patients, because it is better tolerated and has a milder effect. However, it is not equally effective in all cases. For severe neuroses, Novopassit helps better.

Source: https://upraznenia.ru/persen-ili-novopassit.html

How to drink Persen during pregnancy

There have been no studies on the use of Persen during pregnancy. Therefore, Persen is not prescribed to pregnant women. If necessary, the specialist determines the possible risks and benefits. If the benefit to the mother significantly outweighs the possible risk to her and her baby, the drug may be prescribed. The doctor must constantly monitor the condition of the pregnant woman at the time of medication treatment.

Persen should also be taken with great caution during lactation.