Phenotropil is produced in tablets based on the active ingredient – phenotropil. This medication belongs to nootropics that stimulate the action of brain cells and physical activity of a person. The cost of the drug is high, so doctors often prescribe cheap analogues of Phenotropil.
The drug is used to treat the following mental and neurological conditions:
- fast fatiguability;
- memory loss;
- deviations in cognitive functions;
- depression;
- impaired blood flow in parts of the brain;
- abnormalities in brain metabolism;
- intellectual-mnestic disorders;
- convulsive syndrome;
- schizophrenia;
- alcohol addiction;
- sleep rhythm disturbance;
- obesity.
Phenotropil and its analogues in composition are not prescribed in the following cases:
- if you are allergic to the composition of the medicine;
- during the lactation period;
- during pregnancy.
Phenotropil should be taken after eating food to protect the mucous membrane of the digestive tract from destruction. The doctor prescribes the dosage and duration of taking the tablets individually based on the pathology and the stage of its progression. The standard therapeutic regimen is 120-250 mg three times a day. The daily maximum intake of the substance is 750 mg. The last intake procedure should occur no later than 3 pm.
In the first 3-4 days of taking Phenotropil, the following adverse reactions are observed: skin allergies, pressure fluctuations, overexcitation and hot flashes, severe tearfulness and aggression. With further taking of the pills, the patient’s condition returns to normal.
Phenotropil: analogues
05.11.2019 18:23
Fig 1. - Phenotropil USA from the manufacturer SNS Smart Powders
Author: Neurologist Oleg Olegovich Torsky
Phenotropil is considered to be the most popular drug from the group of nootropics, developed by leading pharmaceutical workers. Due to its main active components, the process of blood supply to the brain improves, and the level of concentration and thinking also increases.
The drug Phenotropil is prescribed to people experiencing strong emotional stress, the consequences of which are fatigue, drowsiness, and mental stress.
What to replace it with?
Unfortunately, the nootropic drug Carphedon (phenotropil) has not been produced since 2017. As a result, the question arose among consumers about whether there was a replacement for it. This is due to the fact that many people who have been using this drug for a long period of time have already decided on the required dosage, course of treatment, and breaks. That is why it will be quite difficult for them to get used to another drug, which is a derivative of phenylpiracetam.
Among the analogues of Phenylpiracetam, the following should be highlighted:
- "Braviton" is available exclusively by prescription in the form of tablets. Helps improve blood circulation, reduce platelet aggregation, provide reliable brain protection during hypoxia;
- Vinpocetine improves memory and increases concentration. Indications for use include: traumatic brain injury, encephalopathy, senile dementia;
- "Escotropil" - produced on the basis of piracetam, is aimed at stimulating cognitive processes. The effect on the central nervous system is to change the speed of impulses to the brain, stimulating the metabolic process of nerve cells.
Such drugs belong to the group of psychostimulant drugs. By the way, many people are misled by such names as Phenylpiracetam, Carphedon. It is worth noting that these are just synonyms for modified piracetam.
Pubmed
All information in the article is based on scientific medical materials.
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PubMed is an English-language text database of medical and biological publications created by the US National Center for Biotechnology Information (NCBI) based on the biotechnology section of the US National Library of Medicine (NLM). A key component of PubMed is MEDLINE. It was first introduced in January 1996. Available through NCBI-Entrez[en], a central search engine including PubMed, PubChem and other major medical databases. Contains approximately 25 million citations.
By composition and action
Phenotropil is a drug classified as a mental stimulant. It is worth noting that due to its pronounced stimulating effect, the drug is prohibited for use among athletes before upcoming competitions, since it is considered a type of doping. The main component is the active substance of the same name in an amount of 100 milligrams, which acts as a new generation stimulant, the main task of which is to increase brain activity. In addition to nootropic, it also has the following types of effects:
- anti-anxiety;
- antiamnestic;
- antiepileptic;
- antiasthenic;
- neuromodulatory.
However, the most pronounced effect of Phenotropil is considered to be an improvement in the quality of memory, the learning process, and concentration. By regulating biological rhythms in the brain, increasing the content of aminobutyric acid, dopamine, norepinephrine, and serotonin, the drug helps optimize well-being and improve mood. It is worth noting that the release of the drug ceased in 2021, people are looking for its analogues.
Among the wide variety of nootropic agents that have the same composition as Phenotropil, the following should be highlighted:
- "Entrop";
- "Nootropil" (infusion solution);
- "Slim Stories Prof."
- "Kombitropil";
- "Phenylpiracetam";
- "NooCam."
As for the action, it is worth noting the following analogues of Phenylpiracetam:
- "Ginkgo biloba";
- "Korsavin Forte";
- "Cavinton solution";
- "Picamilon";
- "Aminalon";
- "Glycine";
- "Phenibut";
- "Bilobil Forte";
- "Ginkum".
Picamilon
Manufacturer: AKRIKHIN (Russia)
Release form: tablets
Active ingredient: nicotinoyl gamma-aminobutyric acid
The nootropic drug Picamilon helps dilate blood vessels and improve microcirculation of blood in the brain. This analogue of Phenotropil reduces feelings of anxiety and tension, reduces emotional lability and restores partially lost speech skills. The drug is well tolerated by patients and can be prescribed to children from 2 years of age.
According to active substance
It is worth noting that the main active ingredient of the medicinal nootropic drug is Phenotropil. Among the main analogues of the drug, which have similar components in their composition, the following should be highlighted:
- "Vinpotsetin";
- Acefen;
- "Kavinton"
- "Lutsetam";
- "Vinpotropil";
- "Pirates"
- "Tserakson."
The attending physician, when choosing a phenotropil substitute, must take into account not only the pharmaceutical properties, active substance, indications and contraindications, but also the general health of the patient. The tendency to an allergic reaction, side effects, etc. is also taken into account.
Nanotropil rushing?
According to documents, Nanotropil and Phenotropil always had a mixture of R and S isomers (12). At the same time, the active, “psychostimulating” part is R-, the effects are variable, but how much? What is the probability that Nanotropil will work perfectly? If taken without a doctor's indication, of course)
Data from our survey on Nanotropil: this is not medicine, but the sample turned out to be large. If we discard the answers of those who have not used this substance (79%), it turns out that 28-29% notice a pronounced effect and the same number believe that it is a placebo, the rest, about 43-44%, say that the effect is definitely present, not too strong, but not a dummy either. There are a lot of interesting reviews from real people in the comments; if you want to read them, click here.
It turns out that 71-74% of respondents out of more than 1,500 people speak about more or less strong effects of Nanotropil. When you hear that R-Phenylpiracetam has appeared, then there is a chance that the effectiveness will increase to 90-95%.
According to the instructions, Nanotropil is taken in doses of up to 700 mg per day, more often 100-300 mg after meals. From practice, it was noticed that the effect is stronger if taken in the morning on an empty stomach, 60 minutes before meals with strong insoluble coffee or good green tea.
For memory and performance
Phenotropil is famous for the fact that it has a positive effect on brain cells, thereby stimulating its blood supply. This, in turn, increases concentration, improves memory and significantly increases performance.
Since the drug was discontinued back in 2021, people are constantly looking for suitable substitutes. Among the most popular phenotropil analogues, it is worth noting the following:
- "Nootropil"
- "Biotredin";
- "Calcium hopantenate";
- "Neurobutal";
- "Glycine" and others.
All of the above phenylpiracetam analogues act as the best nootropic mental simulators. They are taken to optimize the processes of blood supply to the brain, improve cognitive functions, that is, for vigor and energy. After a person has taken a specific dose of Phenotropil, his endurance increases under strong emotional stress, tension, and frequent mood swings.
Phenylpiracetam
Manufacturer: OFHK (Russia)
Release form: tablets
Active ingredient: phenylpiracetam
Phenylpiracetam is a nootropic with a pronounced effect on restoring partially lost mnestic functions of the brain (memory, attention, learning ability). The drug improves mood, increases performance and resistance to stress.
During drug treatment, vision and blood supply to the lower extremities improve. The therapeutic effect is noticeable after just a few doses of the medication.
For weight loss
When no methods help to lose weight, including exercise and a balanced diet, women decide to opt for medical weight loss. The drugs include Phenotropil.
Since it has long been discontinued, many are starting to look for substitutes for weight loss. Among them it is worth highlighting such analogues as:
- "Pantogam";
- "Cerebrolysin";
- "Encephabol";
- "Neurodar".
All of the above analogues of phenotropil have properties that accelerate metabolic processes. Experts have found that these drugs eliminate all the symptoms that accompany the feeling of hunger, including:
- increased fatigue and irritability;
- loss of energy;
- significant decrease in performance.
Why discontinued?
Phenotropil was discontinued in April 2021, but the prerequisites for discontinuing its production arose back in 2007. The active substance included in phenotropil was recognized by the Academy of Medical Sciences as outdated and without proven effectiveness. However, the drug was not banned then and within 10 years it was allowed in Russia.
In 2021, the medicine was no longer produced due to the expiration of the license agreement for the patent and trademark “Phenotropil”. This is the official version, which has been producing this drug for many years.
According to the inventors of the drug and its copyright holders, Valentina and Roman Akhapkin, the contract was terminated because the manufacturing company had not improved the active substance of this medicine over many years. Well-known Russian psychopharmacologists plan to improve the formula of the drug and launch it into production again.
In tablets
Phenotropil is a drug from the nootropic group, which is aimed at improving blood supply to the brain and optimizing cognitive functions. The drug is available exclusively in cylindrical tablets in white color. The active substance is a chemical compound called phenyloxopyrrolidinylacetamide (synonymous with the word Phenotropil), the amount of which can vary from 50 to 100 milligrams.
The main substance of the drug Cordafen is quickly absorbed into the gastrointestinal tract. The maximum concentration in blood plasma is observed one hour after administration. Inside, the phenylpiracetam component is not transformed and does not create individual metabolites. The drug is eliminated through the kidneys and intestines. The half-life is about four hours.
Imported
Today, there are a large number of imported drugs that act as analogues of phenotropil. Among them are:
- "Piracetam";
- "Acefen";
- "Cogitum";
- "Vinpotropil";
- "Bravinton".
The above analogues have the same properties as the domestic drug called Phenotropil. The only disadvantage of medicines produced by a foreign manufacturer is the high cost of the drug.
Resumption of production
The issue of resuming the production of phenotropil has been discussed for a long time and there has still been no clear information on this matter, only speculation and conjecture.
For the first time, group representative S. Chaplenko officially announced that production of the drug would be resumed in 2021 in March. But now the drug will have a new name, phenylpiracetam. She explained that the drug must undergo all quality control procedures and appear in pharmacies in the second half of 2021. But the production start date was not announced.
Already in April 2021, the antimonopoly service gave permission to release this drug. It is now known who produces Phenylpiracetam. Its new manufacturer is the Obninsk Pharmaceutical Company. The drug fonturacetam belongs to the group of nootropic drugs and has the same spectrum of action as phenotropil.
The best
Sometimes there is a need to replace Phenotropil with a more effective option. Today, this is due to the fact that this drug is simply not available on the pharmacy window. Among the most powerful drugs that are analogues of phenotropil, it should be noted:
- "Cavinton";
- "Nootropil";
- "Lutsetam" and others.
It is worth noting that even the best analogue cannot completely replace the original medicine, since the main component can be supplemented with several additional substances.
