Good afternoon, many will be interested in understanding their health and their loved ones, and I will tell you my experience, and we will talk about WHAT THE MEDICINES BETASERC, BETAVER, VESTIBO ARE DIFFERENT. Most likely, some details may differ, as was the case with you. Please note that you should always consult with highly specialized specialists and not self-medicate. Naturally, you can quickly find the answer to the simplest questions and diagnose yourself. Write your questions/suggestions in the comments, and together we will improve and supplement the quality of the material provided.
The pharmacist-editor of Pharmacy “Tell A” LLC answers your questions. The main principles of the Pharmacy are reliability, professionalism, quality assurance of medicines and all products, polite and fast service.
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The pharmacist-editor of Pharmacy “Tell A” LLC answers your questions. The main principles of the Pharmacy are reliability, professionalism, quality assurance of medicines and all products, polite and fast service.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
An artificial analogue of histamine . The effect of betahistine has not been fully studied. There are only a number of hypotheses confirmed by clinical data:
- active substance – partial stimulator of H1-histamine receptors and blocker of H3-histamine receptors of the vestibular centers of the nervous system; improves histamine metabolism and its release due to the above properties;
- betahistine increases blood circulation in the inner ear, relaxing vascular sphincters in this area, and also enhances microcirculation in the brain;
- betahistine stimulates restoration of vestibular function after vestibular neurectomy in animals and humans;
- dose-dependently reduces the generation of impulses in neurons of the vestibular nuclei.
The therapeutic effect of betahistine was demonstrated in patients with Meniere's syndrome and vestibular vertigo , which was expressed by a decrease in the severity and frequency of dizziness .
Pharmacokinetics
When taken orally, the active substance is actively absorbed from the intestine and is almost completely transformed to form a derivative of 2-pyridylacetic acid. The content of betahistine in the blood is low.
Concomitant food intake may slow down the absorption of betahistine. Reaction with blood proteins does not reach the 5% barrier. The maximum concentration of 2-pyridylacetic acid in the blood occurs 1 hour after consumption. The half-life is approximately 3 and a half hours.
The metabolite is actively evacuated in the urine. Excretion of betahistine itself through the kidneys or intestines is negligible.
Comparison of safety of Betaver and Betaserc
The safety of a drug includes many factors.
At the same time, Betaserk’s is higher than Betaver’s. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing metabolism in Betaserc, as well as in Betaver, we look at which organ is the metabolizing organ and how critical the effect on it is.
The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Betaserc has fewer risks when used than Betaver.
Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Betaserc and Betaver.
Indications for use of Betaserc
Indications for use of Betaserc:
- Meniere's disease;
- vertebrobasilar insufficiency , atherosclerosis of the cerebral arteries , post-traumatic encephalopathy (as a component of complex therapy);
- syndromes characterized by tinnitus, increasing hearing loss, dizziness , including hydrops of the inner ear , labyrinthine and vestibular disorders, labyrinthitis , vestibular neuritis, benign positional vertigo.
Comparison of addiction between Betaver and Betaserc
Like safety, addiction also involves many factors that must be considered when evaluating a drug.
So, the totality of the values of such parameters as “o syndrome” in Betaver is quite similar to the similar values in Betaserc. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Betaver has quite a small amount of “syndrome”, just like Betaserc.
Betaserc tablets, instructions for use (Method and dosage)
The medicine is prescribed to be taken orally with meals. The dosage is selected individually, taking into account the response to therapy.
The daily dose for adults is usually 24-48 mg, divided into 2-3 doses. The 16 mg or 24 mg tablet is easy to split. To do this, place the dosage form on a hard surface with the notch facing up and press firmly on it with your finger.
Sometimes the drug shows its effect only after 2-3 weeks of treatment, and a confident therapeutic effect develops after several months of constant use. No dosage adjustment is required in elderly patients.
Comparison of the effectiveness of Betaver and Betaserc
Betaserc is more effective than Betaver - this means that the ability of the drug substance to provide the maximum possible effect is different.
For example, if the therapeutic effect of Betaserc is more pronounced, then it is impossible to achieve this effect with Betaver even in large doses.
Also, the speed of therapy is an indicator of the speed of the therapeutic action; Betaserc and Betaver are also different, as is bioavailability - the amount of a drug reaching the place of its action in the body. The higher the bioavailability, the less it will be lost during absorption and use by the body.
Betaserc's analogs
Level 4 ATX code matches:
Betagis
Stugeron
Betaver
Westinorm
Westicap
Betagistine
Tagista
Vestibo
Cinnarizine
- Betagistine
- Alfaserk
- Microzer
- Asniton
- Betaver
- Betacentrin
- Vertran
- Vestibo
- Westinorm
- Westicap
- Denoise
- Vazoserk
- Tagista (Russian equivalent)
The price of Betaserc analogues is noticeably lower than the price of the described drug.
Betaserc and its analogues (the vast majority) contain betahistine as an active substance, so their indications and contraindications will be identical.
Which is better: Betaserc or Betahistine?
Betahistine and the described drug are analogues with an identical active component. Their indications and contraindications are also the same. The choice should be made based on economic feasibility.
Betaserk or Vestibo – which is better?
Vestibo is a cheaper analogue of Betaserc with almost the same composition. The choice between these drugs should be made for reasons of economic feasibility.
Tagista or Betaserk – which is better?
Tagista is the Russian analogue of Betaserk. The main difference is the price: Tagista rightfully takes the place of the most affordable medicine containing betahistine.
Comparison of side effects of Betaver and Betaserc
Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.
Betaver's rate of adverse events is almost the same as Betaserc's. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Betaver are similar to Betaserc: how quickly the body recovers after taking it and whether it recovers at all.
Betaserk price, where to buy
The price of Betaserc 24 mg No. 20 on average in Russia is about 500 rubles, and the drug with a dosage of 16 mg No. 30 is 600 rubles.
In Ukraine, the price range is wide: a package of medicine with a dosage of 16 mg No. 30 can be bought for about 400 hryvnia.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
- Online pharmacies in KazakhstanKazakhstan
LuxPharma* special offer
- Betaserc tablet.
24 mg 20 pcs 950 rub. order
ZdravCity
- Betaserc Long tablets 48 mg 28 pcs. JSC Veropharm
1120 rub. order
- Betaserc tab. 24 mg No. 60 JSC Veropharm
RUB 1,276 order
- Betaserc tab. 16mg No. 30AO Veropharm
RUB 613 order
- Betaserc tab. 24mg No. 20AO Veropharm
RUR 556 order
- Betaserc Long tablets 48 mg 56 pcs. JSC Veropharm
RUB 1,908 order
Pharmacy Dialogue
- Betaserc tablets 24 mg No. 20Abbot
RUR 542 order
- Betaserc (tab. 16 mg No. 30) Abbot/Veropharm
620 rub. order
- Betaserc tablets 16 mg No. 30Abbot/Veropharm
RUR 627 order
- Betaserc tablets 24 mg No. 60Abbot/Veropharm
RUB 1,301 order
- Betaserc tablets 8 mg No. 30Abbot/Veropharm
RUR 429 order
show more
Pharmacy24
- Betaserc 8 mg N30 tablets Abbott Healthcare SAS., France
376 UAH order - Betaserc 16mg N30 tablets Mylan Laboratories SAS, France
423 UAH. order
PaniPharmacy
- Betaserc tablets Betaserc tablets 24 mg No. 20 France, Mylan Lab.
418 UAH. order
- Betaserc tablets Betaserc tablets 16 mg No. 30 France, Mylan Lab.
429 UAH. order
- Betaserc tablets Betaserc tablets 8 mg No. 30 France, Mylan Lab.
432 UAH. order
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Betaserc drug for cervical osteochondrosis
Reviews from experts report that the use of the drug in question for osteochondrosis of the cervical spine makes sense only in the presence of vertebrogenic cervicocranialgia or vertebral artery syndrome.
As you know, with this disease, the patient very often experiences painful symptoms in the form of double vision, dizziness, instability in a standing position, etc. Such signs are caused by compression of the arteries that bring blood to the brain structures. Because of this, there is insufficient blood supply, which causes all the symptoms listed above. Therefore, to treat such disorders, many people with osteochondrosis take Betaserc tablets.
What is the difference?
Contraindications
| Betaserk | Betagistine |
| [General] Hypersensitivity to any component of the drugs; up to 18 years old; pregnancy and lactation; pheochromocytoma; bronchial asthma; gastric and duodenal ulcers in the acute phase (with caution during remission). | |
| — | Lactose intolerance. |
Another difference between Betaserc and Betahistine is the cost of the drugs. Imported ones are more expensive. For example, Betaserc (16 mg) 30 tablets costs about 550 rubles, and the same package of Betahistine from a domestic manufacturer costs approximately 5 times less.
30 tab. (France)
Considering the significant variety of causes that cause vertigo, the complexity and multicomponent nature of therapy, the decision when choosing Betaserc and Betahistine - which is better - must be agreed with a specialist. The doctor will help you choose the right dose of the drug and the course of its administration. Do not forget that uncontrolled treatment can harm your health.
The multidirectional effect of betahistine on H-receptors determines the variety of its biological effects, which include:
What are they prescribed for and how do they work?
We often use antihistamines to treat allergic reactions. However, histamine, in addition to participating in immunological reactions, is a substance that regulates various brain functions. Histamine and its three types of receptors (H1, H2 and H3) are widely represented in the vestibular system, therefore antihistamines and histamine-like drugs are recognized as effective in the treatment of vertigo.
30 tab. (Russia)
Betahistine is a structural analogue of histamine that has been used as a medicinal agent for about 40 years. It has been established that betahistine acts differently on histamine receptors:
- is a weak H1 agonist (repeats the action of histamine),
- is a strong H3 antagonist (acts opposite to histamine),
- has virtually no effect on H2.
The multidirectional effect of betahistine on H-receptors determines the variety of its biological effects, which include:
- increased cochlear blood flow,
- vasodilation of peripheral vessels,
- increased vascular permeability and decreased blood pressure,
- impact on sensory cells of the vestibular apparatus,
- increased histamine synthesis in histaminergic neurons,
- changes in the excitability of neurons of the vestibular system.
Thus, the effect of betahistine is not limited to the effect on the blood supply to the vestibular apparatus. It turned out that it is just as effective in the treatment of vestibulopathies not associated with vascular insufficiency. It is usually well tolerated and rarely causes unwanted side effects. In addition, it is devoid of sedative effects.
A recent study showed that honey. preparations containing betahistine are an indispensable component of treatment protocols for Meniere's disease and other vestibulopathies in European clinical practice and are prescribed in 94% of cases.
In a double-blind, randomized study conducted recently in 11 clinics in Italy, 144 patients with peripheral vestibular vertigo were observed. One group received a placebo for 3 months, and the other received 8 mg of betahistine twice a day. Clinician ratings of treatment were very good in 74% of patients taking the drug, compared with 27% of patients taking placebo.
The effectiveness has been confirmed in other studies. In 293 examined patients with Meniere's disease, symptoms of dizziness disappeared altogether or the frequency and intensity of attacks decreased in 93% of patients when taking 16 mg of betahistine three times a day for 3 months.
Vestibulopathy associated with dizziness is a serious problem. You will be surprised, but there are more than fifty reasons that cause the symptom of dizziness (vertigo). Nausea and vomiting as accompanying symptoms are also common. Is there a way to get off this “carousel” and finally feel that the world around you no longer revolves around you?
Treatment of such diseases usually proceeds in two stages. At the first stage, the patient is offered vestibular suppressants that block vertigo, after which they move on to the stage of compensation for disorders and rehabilitation of the vestibular apparatus. It is at this stage that the drugs Betahistine and Betaserc can be used. Let's look at their main properties and differences.
Both drugs belong to the same pharmacological group, because they basically contain the same active ingredient betahistine
. Since these drugs are analogues, the question of how Betaserc differs from Betahistine can only be attributed to the manufacturer.
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Betaserc is produced in the form of tablets of 8, 16 and 24 mg by Abbott Healthcare Products BV (Netherlands or France). Betahistine in the same form and dosage is produced in Russia at many pharmaceutical sites, including Kanonpharma Production ZAO, VERTEX, North Star.
