The first trimester of pregnancy is the period from the first day of the last menstruation to the thirteenth week (obstetric period). At this time, the laying of the vital organs of the fetus occurs, so a woman should be very attentive to her health and well-being.
From the first days of pregnancy, or better still at the stage of planning conception, a woman should give up cigarettes, alcohol, and heavy physical work. Mandatory conditions for bearing a healthy baby are proper nutrition, proper rest and, of course, compliance with all prescriptions of the gynecologist.
Special attention should be paid to the prevention of vitamin deficiency. Deficiency of vitamins and minerals has a very bad effect on both the development of the fetus and the course of pregnancy. Therefore, it is advisable to take a specialized vitamin and mineral complex for pregnant women from the first trimester or even before pregnancy.
What is Glycine
One of the nonessential simplest amino acids, which is also a central neurotransmitter. Glycine is a component of protein, produced in the body and supplied to it from the outside with food. In its pure form it is a fine-crystalline white powder. It ensures the conduction of nerve impulses, regulates brain activity, has a sedative effect, and prevents the development of muscle dystrophy.
In the pharmaceutical industry, the biotic drug is produced in the form of lozenges:
- Glycine: white tablets containing 100 mg of active ingredient, 50 pcs. in cell blisters;
- Glycine Bio: white tablets, flat-cylindrical, uncoated, 50 or 100 mg of active ingredient per tablet, packaged in 10–100 pieces in plastic bottles or cell blisters;
- Glycine Forte Evalar: yellow tablets with lemon flavor, contain 600 mg of glycine, vitamins B1, B6, B12.
Additional components of the drugs: soluble MCC, magnesium stearate, povidone.
Glycine enhances protective inhibition in the central nervous system, reducing mental and emotional stress. The drug improves brain performance, neutralizes the effects of toxins on it, and prevents the progression of nervous system disorders due to injuries and ischemia. Glycine eliminates signs of vegetative-vascular disorders, helps you fall asleep easily, and normalizes sleep quality.
Glycine has an affinity for the cells of the body, is quickly absorbed through the mucous membranes, and is distributed in all fluids and tissues. The drug does not form deposits, is non-toxic, breaks down into carbon dioxide and water.
Benefits for pregnant women
Glycine is an aminoacetic acid. This substance is produced by the human body, regulates the metabolic processes of cells of the nervous system and brain, and normalizes their functioning. The amino acid has both neurotransmitter and neuroprotective effects. It helps women during pregnancy to alleviate the following conditions:
- constant change of mood;
- sleep disturbance;
- emotional instability, hysterics, tearfulness, moodiness;
- stress.
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Glycine is useful for pregnant women to take, as it helps to calm down, and also relieves stress, depression, improves mood, and brain activity. The substance relieves vegetative-vascular disorders that may occur when carrying a child, normalizes blood pressure, relieves headaches, dizziness, lethargy, drowsiness, and increases performance.
Note! The drug based on aminoacetic acid prevents the destruction of neurons and has an antitoxic effect, which helps normalize the functioning of the central nervous system.
Watch a video with detailed information about glycine:
Glycine tablets instructions, what they are for, reviews.
When and how to take Glycine
The drug is indicated for:
- stress;
- psycho-emotional breakdowns, neuroses;
- high mental stress;
- diseases that provoke nervousness, insomnia;
- alcohol withdrawal syndrome;
- behavioral deviations in children and adolescents;
- ischemic transient attacks, stroke.
The drug is taken on an empty stomach, before or after meals. The presence of food in the stomach does not affect the absorption of glycine. The tablets are placed under the tongue or buccally - between the gum and lip. Contact of the drug with the mucous membrane is necessary. There is no need to chew or swallow it; you just need to wait until it is completely dissolved in your mouth. Glycine does not require drinking water.
The daily dose for adults is from 100 to 1000 mg, depending on health problems. General recommendation for use for adults: 1 tablet. 2–3 times a day.
Is it possible to get by with food sources?
Amino acid deficiency affects the state of the nervous system, so it must be replenished either with medications or sources. Women carrying a child are recommended to use the latter option, as it is safer.
Table - Products containing aminoacetic acid
| Food sources | Content, mg/100 g |
| Egg white | 2,8 |
| Soya beans | 1,9 |
| Pumpkin seeds | 1,8 |
| Pig tongue | |
| Parsley | |
| Rabbit meat | 1,6 |
| Veal, beef liver | |
| Peanut | 1,55 |
| Pork liver | 1,5 |
| Mussels | 1,48 |
But these products will not be able to normalize the psychological state during frequent stress and severe hormonal imbalance. For such disorders, it is better to take a drug based on aminoacetic acid.
How to choose the best sedative
There are many drugs containing aminoacetic acid on the pharmaceutical market. But not all remedies are effective. Therefore, when choosing a drug, we recommend paying attention to the following nuances:
- Concentration of the active component. There are tablets with a dosage of 0.1; 0.2; 0.3 and 0.5 g. Preparations with a minimum concentration of amino acids are safe for pregnant women.
- Active composition. In addition to glycine, the medicine may contain B vitamins, magnesium, and other substances. Such drugs can also be taken by expectant mothers, but only as prescribed by a doctor.
- Auxiliary staff. The fewer foreign substances, the better. The presence of methylcellulose and magnesium stearate is allowed.
- Release form. Most of the products are presented in tablets. They are sweet and easy to use. But there are also capsules and powder. The latter is the safest because it does not contain foreign impurities.
- Manufacturer. Not all well-known companies produce a high-quality drug. Therefore, it is first recommended to collect information about its manufacturers and find out which of them the majority of buyers speak well of.
Structural and functional analogs of glycine allowed during pregnancy
If, for objective reasons, it is impossible for the expectant mother to take glycine, the doctor selects analogues that are structural (as identical as possible in composition) or functional, having a similar effect on the body.
Table: glycine analogues
| Drug name | Compound | Release form | Contraindications | Features of application | Price |
| Tenoten | Active substance - antibodies to the brain-specific protein S-100, affinity purified - 0.003 g. Additionally:
| Lozenges |
| Due to its brain-stimulating effect, it is recommended to take the drug no later than two hours before going to bed. If you are pregnant, consult a doctor before use. | From 220 rubles |
| Homeostresses | Active ingredients:
Auxiliary components:
| Homeopathic lozenges |
| The drug is approved during pregnancy, but the decision to take and adjust the dose should be discussed with a doctor. It is not recommended for use by people intolerant to sucrose, lactose and fructose. Patients with diabetes should be extremely careful and not self-medicate. | From 293 rubles |
| Biotredin | Active substances:
Additionally:
| Lozenges |
| Biotredin increases brain activity, so it conflicts with drugs that have a sedative effect. When prescribing a therapeutic course, the doctor must take this feature into account. | From 103 rubles |
| Valerian extract | Active substance - extract from the roots and rhizomes of Valerian - 0.02 g. | Tablets for oral administration |
| During pregnancy, you should not use valerian without your doctor's approval. It is forbidden to exceed the prescribed dose and take the drug simultaneously with other sedatives. | From 25 rubles |
| Motherwort extract | The active substance is motherwort extract. Auxiliary components:
| Tablets for oral administration |
| Widely used in gynecological practice for uterine hypertonicity and other conditions dangerous during pregnancy. Before use, consult a doctor. | From 17 rubles |
| Glycine MHPP | The main substance is aminoethanoic acid - 100 mg. Additives:
| Lozenges | allergic reactions to the composition of the drug | The composition is identical to the classic recipe of the Biotiki enterprise. Allowed for expectant mothers as prescribed by a doctor. | From 24 rubles |
In what cases are sedative tablets prescribed for pregnant women?
The main indications for the use of Glycine during pregnancy are:
- increased psycho-emotional stress;
- decreased intellectual abilities;
- sleep disorders;
- absent-mindedness, memory impairment:
- intense mental work;
- stressful situations;
- feeling of causeless anxiety;
- cardiovascular pathologies.
When is Glycine contraindicated for pregnant women?
Only a doctor should prescribe any medications. In addition, the specialist monitors the effects of the products on the expectant mother’s body after assessing her condition. As a rule, Glycine has no special contraindications for use. It is not recommended to take it if allergic reactions occur. High dosages of the drug can provoke a collaptoid state. Insufficient blood flow to the brain can cause fetal hypoxia. Glycine should be used with caution:
- with sensitivity and intolerance to the components of the drug;
- with low blood pressure, since the medicine can lower it even more.
Indications for prescribing glycine to expectant mothers
Most often, doctors prescribe the drug to pregnant women who have the following conditions:
- high blood pressure. Not all popular drugs for lowering blood pressure are approved when carrying children, and this pathology is not uncommon during pregnancy;
- problems with memory and attention;
- neuroses and hysterics;
- instability in the emotional sphere, a tendency to tearfulness or aggression due to the effects of hormones;
- difficulty falling asleep and sleep disorders;
- encephalopathy in pregnant women;
- intrauterine hypoxia;
- gestosis and placental insufficiency;
- motor activity that is difficult to control;
- consequences of traumatic brain injuries.
If you don’t want to take glycine in tablets, then know that it is found mainly in animal products, including meat, fish, poultry and dairy foods.
When to start taking
Many women ask doctors whether it is possible to drink glycine in the early stages of pregnancy, because some sedative medications during this period can harm the fetus. If the expectant mother experiences strong emotional stress, increased irritability, nervousness, tearfulness, then she can take aminoacetic acid, but only under the supervision of a doctor.
Attention! Glycine is recommended for use at the stage of planning conception for women who suffer from moral exhaustion and neuroses.
Overdose
An overdose of glycine during pregnancy can cause harm not only to the woman’s body, but also to the developing fetus. It manifests itself with the following symptoms:
- lowering blood pressure;
- headache;
- apathy;
- drowsiness;
- dizziness;
- attacks of suffocation, as well as severe coughing;
- causeless appearance of anxiety, fear.
If large doses of the medicine have been taken, it is necessary to take the sorbent and immediately call an ambulance.
Until when to drink
When carrying a child, the drug should not be taken for a long time. The maximum duration of the course is 2-3 weeks, then you need to take a break for 2-3 months. In the second trimester, there is often no need to take a sedative, as the hormonal levels stabilize. But if a woman is constantly under stress, then she should repeat the course, since any mental state of the expectant mother affects the development of the fetus.
Attention! The amino acid can be taken as a sedative in the third trimester (2-3 months before giving birth).
Features of the use of glycine during pregnancy
The duration of the course and the required dosage are selected by the doctor individually for each patient, focusing on her symptoms. For example, if you are in an overly depressed state, you may be prescribed 2 or 3 tablets per day for two weeks. And for those who have problems falling asleep, one glycine tablet 30 minutes before bedtime is enough. The maximum daily dose is 300 mg.
The main condition is not to swallow the tablets, but to dissolve them between the upper lip and gum (buccally) or by placing them under the tongue. The effect occurs faster and is more pronounced. In no case should you exceed the recommended dosage; glycine is still a medicine, not a candy.
Although I am not pregnant, I will share my own experience of taking glycine. The doctor prescribes glycine to me 1-2 times a year to calm my nerves after an injury. After taking the course, I find myself becoming calmer and lashing out at loved ones less. It’s just that I spend a day after finishing the treatment in bed, unable to get up, although attacks of insomnia are common between courses. My advice to those who work is to start drinking glycine so that the last day of taking it falls on Friday. Despite the fact that increased sleepiness after stopping use is an individual characteristic of the body, it is better to be safe and have the opportunity to get enough sleep on the weekend. In the middle of the work week, such a chance is unlikely to arise.
Where can I buy
This drug is available without a prescription. But at an affordable price, you can buy it at a pharmacy or order it online.
The lowest prices for glycine are in the well-known online store iHerb. From other sellers the cost will be 30-50% higher. You can check it yourself.
There is a discount of up to 10% on iHerb using this promotional code:
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The promotional code is activated in the cart after adding the 1st product and is valid only for the 1st order.
Side effects and allergies
Glycine should be taken with caution during pregnancy. The drug contains not only aminoacetic acid, but also auxiliary components that can cause allergies.
Attention! It is recommended to start taking the drug with small doses.
The following symptoms may indicate the development of an allergic reaction:
- itching, skin rashes;
- lacrimation, redness of the mucous membranes of the eyes;
- sneezing, runny nose, cough;
- Quincke's edema.
Other effects may also appear in the form of decreased blood pressure, increased nervous excitability or lethargy. But these adverse reactions occur rarely.
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